Skip to main content

Phoenix processing a revolution ???

The Phoenix lander has succeeded beyond the hopes of its designers and has not only successfully landed on Mars near the ice cap but has managed to unearth (or unmars to be precise) frozen ice just under the soil surface near the lander. Now the lander undergoes the process of chemical analysis of the ice to determine if it has anything in it that we might consider as a form of life. It is amazing that we are in a position to answer the question of weather or not life is unique to our blue orb, at the same time the relative silence in the media is disturbing. I think the most important consequence of a discovery of living entities in the Martian subsurface ice would be the ability to adjust our estimates for the probability of life in the Galaxy.

We've known since the 50's that the elements of life, simple amino acids , lipids can be formed by simulation of conditions similar to what was found in the early Earth. However, amino acids do not life make, before we get to life we need to have complex replicating chains of Amino Acids , called RNA ...and then we need protective shells for these RNA that are able to be permeated conditionally based on various interactions with materials outside of the membrane....in essence a primitive cell. Finding such entities on Mars would indicate that the process of building life is one that can form in the most inhospitable environments and should drastically increase the estimates for life in the Galaxy. Still it must be pointed out that life being able to form in extreme environments does not necessarily lead to life that can evolve to the complex form that we exist in, it could be that our form of life, introspective life is orders of magnitude more improbable to emerge from cell based life , leaving most of the galaxy one big petri dish of goo populated by the occasional macroscopic animal forms like ourselves only in rare occasions.

Still it is exciting to know that we are on the virge of finding out, it just may be that the results yield nothing interesting but that would not end the game, the solar system has several planetary bodies which have complex geothermal activity and chemistry that could be the seat of bizarre forms of life, such as the frozen moon of Saturn's Enceladus which is blessed with so much water it spews it into space in massive geysers that are now believed to be the source of one of Saturn's rings. Could Enceladus be spewing out more than just liquid to populate that ring? The preponderance of the materials that constitute living things in the solar system provides confidence that very interesting chemistries are being tried or have been tried and we know it happened at least once so it is possible that it could happen again.

Hopefully the experiments being conducted by Phoenix will answer that question definitively very soon.

http://en.wikipedia.org/wiki/Miller-Urey_experiment

http://en.wikipedia.org/wiki/Enceladus_(moon)

Comments

Popular posts from this blog

the attributes of web 3.0...

As the US economy continues to suffer the doldrums of stagnant investment in many industries, belt tightening budgets in many of the largest cities and continuous rounds of lay offs at some of the oldest of corporations, it is little comfort to those suffering through economic problems that what is happening now, has happened before. True, the severity of the downturn might have been different but the common factors of people and businesses being forced to do more with less is the theme of the times. Like environmental shocks to an ecosystem, stresses to the economic system lead to people hunkering down to last the storm, but it is instructive to realize that during the storm, all that idle time in the shelter affords people the ability to solve previous or existing problems. Likewise, economic downturns enable enterprising individuals and corporations the ability to make bold decisions with regard to marketing , sales or product focus that can lead to incredible gains as the economic ...

How many cofactors for inducing expression of every cell type?

Another revolution in iPSC technology announced: "Also known as iPS cells, these cells can become virtually any cell type in the human body -- just like embryonic stem cells. Then last year, Gladstone Senior Investigator Sheng Ding, PhD, announced that he had used a combination of small molecules and genetic factors to transform skin cells directly into neural stem cells. Today, Dr. Huang takes a new tack by using one genetic factor -- Sox2 -- to directly reprogram one cell type into another without reverting to the pluripotent state." -- So the method invented by Yamanaka is now refined to rely only 1 cofactor and b) directly generate the target cell type from the source cell type (skin to neuron) without the stem like intermediate stage.  It also mentions that oncogenic triggering was eliminated in their testing. Now comparative methods can be used to discover other types...the question is..is Sox2 critical for all types? It may be that skin to neuron relies on Sox2 ...

AgilEntity Architecture: Action Oriented Workflow

Permissions, fine grained versus management headache The usual method for determining which users can perform a given function on a given object in a managed system, employs providing those Users with specific access rights via the use of permissions. Often these permissions are also able to be granted to collections called Groups, to which Users are added. The combination of Permissions and Groups provides the ability to provide as atomic a dissemination of rights across the User space as possible. However, this granularity comes at the price of reduced efficiency for managing the created permissions and more importantly the Groups that collect Users designated to perform sets of actions. Essentially the Groups serve as access control lists in many systems, which for the variable and often changing environment of business applications means a need to constantly update the ACL’s (groups) in order to add or remove individuals based on their ability to perform cert...