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Showing posts from September, 2014

iPSC: Embryonic "base class" generation method found.

In another ground breaking advance to the science of stem cell pluripotent modification a team of researchers has succeeded in inducing a cell to change into the earliest known embryonic state.

This is great news as it is exactly what would need to be possible so that full comparative analysis between different cell lines induced into creation can be had. Comparative analysis will then enable the key genes that differentiate different stem cell types for different tissues to be genetically characterized and once that happens the ability to point genetically shift cells from type to type (even post differentiation) will be possible.

This is a hugely important feat because it isolates an ability to identify from the zoo of genes the specific pathway expressions that crystalize the cells that constitute living organisms and enable their macroscopic functions.

The sequencing of any given genome gives one a book filled with words but no chapter titles or division labels. All the words bei…

Illusion of continuity: consciousness vs quantum electro dynamics

You know one thing I've been thinking about in the last few days....

It is of the solution that Feynman came up with for describing quantum electrodynamics and resolving a whole host of problems which up to that time were intractable.

The integration of renormalization into the theory and the first class representation of histories of evolution for particle dynamics that spanned the present the future and the past in the wave function description.

I asserted a few days ago that so far as enabling the mathematical resolution there is no proof that any real particles can travel backward in time...some mathematical tools are just that and despite being useful should never be expected to be "realized".

A good example of this from mathematics and engineering is the complex plane and the astonishing landscape of possibility it opened up. What is "i" ??

In the same way that a particles history can be seen as a present position that emerged from an infinite set of pos…

Big Business: Where Innovation goes to starve.

A recent medium post contained the following quote:

"I promise you, my reaction to the project’s cancelation wasn’t “Too bad, let me find my next longshot!” It was more like grief that a year of my life had been wasted, guilt that I’d wasted the efforts of my team, fear of reputation damage, and determination to work on something next time that would actually matter.

As individuals, we have no portfolio strategy — so those 10% odds are no longer palatable. When we fail, most rational people respond by trying to avoid dumb ideas and pick smart bets with clear impact the next time. People who happen to have a hit in their first few tries are even more vulnerable to the belief that they have to succeed every time (and take it harder when subsequent failures inevitably occur.) And that’s it — the dead-end for innovation.

I’ve met a few people who don’t seem to have this reaction (serial entrepreneurs every one of them) and I can’t tell you what makes them react differently or how to le…